vasoactive intestinal polypeptide (VIP); [precursor contains: intestinal peptide PHV-42; intestinal peptide PHM-27; peptide histidine methioninamide 27; vasoactive intestinal peptide]

Function

• peptide neurotransmitter & hormone involved in appetite & satiety
• causes vasodilation
• lowers arterial blood pressure
• stimulates myocardial contractility
• increases glycogenolysis
• relaxes the smooth muscle of trachea, stomach & gall bladder

Structure

• belongs to the glucagon family

Compartment

• secreted

Alternative splicing

named isoforms=2

Pathology

• VIP is secreted by VIPomas

More general terms

• secretin family peptide
• neurotransmitter
• gastrointestinal hormone

Additional terms

• vasoactive intestinal polypeptide [VIP] receptor

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7432
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7432
• OMIM: https://mirror.omim.org/entry/192320
• UniProt: http://www.uniprot.org/uniprot/P01282.html