zinc deficiency
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Etiology
- see serum Zn+2
- there are no stores of Zn+2 in the body
- Crohn's disease
Pathology
- delayed wound healing
- impaired immune function
Clinical manifestations
- growth retardation
- alterations in taste & smell
- hypogonadism in males
- hepatosplenomegaly
- geophagia
- diarrhea
- alopecia
- dermatitis[4] (images) erythematous, vesiculobulous, pustular
Management
- zinc supplementation
- RDA is 15 mg/day
- 50 mg/day is probably safe
- excessive zinc supplementation coincident with marginal copper status may be associated with sudden cardiac death[2]
More general terms
Additional terms
References
- ↑ Bakerman's ABC's of Interpretive Laboratory Data Bakerman S, Bakerman P, Strausbach P Interpretive Laboratory Data In, Scottsdale 2002
- ↑ 2.0 2.1 Spencer JC. Direct relationship between the body's copper/zinc ratio, ventricular premature beats, and sudden coronary death. Am J Clin Nutr. 1979 Jun;32(6):1184-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/443186
- ↑ Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
- ↑ 4.0 4.1 Schroder SD, Griebl SW Images in Clinical Medicine, Zinc Deficiency-Associated Dermatitis. N Engl J Med 2020; 383:e103. Oct 29 https://www.nejm.org/doi/full/10.1056/NEJMicm2003516
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022