measles & rubella combined vaccine (M-R-VAX II)

Indications

• simultaneous immunization against measles & rubella
• measles-mumps-rubella vaccine (MMR) is the preferred vaccine for most children & many adults

Contraindications

• immunodeficiency
• pregnancy

Dosage

Children > 15 months & adults: 0.5 mL SC

Injection: 1000 TCID50 each of:

• live attenuated measles virus vaccine
• live rubella vaccine

Adverse effects

• common (> 10%)
  • fever < 100 F
  • burning at site of injection
  • arthralgias
  • local tenderness & erythema
  • urticaria
  • rash
• less common (1-10%)
  • fever 100-103 F, delayed-type allergic reaction, malaise, headache, sore throat, lymphadenopathy
• uncommon (< 1%)
  • difficulty breathing, hives, itching, reddening of skin (especially around eyes & ears), tiredness, convulsions, encephalitis, confusion, severe headache, stiff neck, vomiting, diplopia, thrombocytopenic purpura, prolonged fever > 103 F, optic neuritis, hypersensitivity

* Also see individual components:

More general terms

• live virus vaccine

Additional terms

• measles virus vaccine, live, attenuated (Attenuvax)
• measles, mumps & rubella combined vaccine (MMR)
• rubella virus vaccine, live (Meruvax II)