disease interaction(s) of epilepsy with cardiovascular events

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^[1]

Pathology

of the cardiovascular events, strong enzyme-inducing anticonvulsant appear to have the largest effect on myocardial infarction (59%)

Pharmacology

association between epilepsy & cardiovascular events in elderly largely due to enzyme-inducing anticonvulsants ^[1]
- strong enzyme-inducing anticonvulsants include:
  - carbamazepine, phenytoin, phenobarbital, & primidone
- weak enzyme-inducing anticonvulsants include:
  - oxcarbazepine, eslicarbazepine, topiramate, & rufinamide

More general terms

disease interaction

References

↑ ^1.0 ^1.1 Li J, Shlobin NA, Thijs RD et al Antiseizure Medications and Cardiovascular Events in Older People With Epilepsy. JAMA Neurol. 2024 Sep 30. PMID: https://www.ncbi.nlm.nih.gov/pubmed/39348143 https://jamanetwork.com/journals/jamaneurology/fullarticle/2824203

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