GrimAge; DNAm GrimAge
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Introduction
- GrimAge is a composite biomarker of aging based on 7 or 8 DNA methylation surrogates including a DNA methylation-based estimate of smoking pack-years[1]
- GrimAge is an epigenetic clock with predictive ability for life expectancy
- GrimAge estimates of levels of plasma proteins including
More general terms
References
- ↑ 1.0 1.1 1.2 1.3 Lu AT, Quach A, Wilson JG et al DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY). 2019 Jan 21;11(2):303-327. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30669119 PMCID: PMC6366976 Free PMC article.
- ↑ 2.0 2.1 Lu AT, Binder AM, Zhang J et al DNA methylation GrimAge version 2. Aging (Albany NY). 2022 Dec 14;14(23):9484-9549. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36516495 PMCID: PMC9792204 Free PMC article.