disease interaction(s) of inflammation with aging
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Introduction
Interactions:
- chronic systemic inflammation predicts immunological health in the elderly[1]
Clinical significance
- inflammatory marker chemokine CXCL9 upregulates multiple genes implicated in inflammation & is involved in cellular senescence, vascular aging & adverse cardiac remodeling[1]
More general terms
References
- ↑ 1.0 1.1 1.2 Buck Institute for Research on Aging 'Clock' created to predict immunological health and chronic diseases of aging Research highlights the critical role of the immune system in the aging process. Science Daily. Science News. July 12, 2021 https://www.sciencedaily.com/releases/2021/07/210712122159.htm
Sayed N, Huang Y, Nguyen K et al An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Nature Aging 2021 Not indexed in PubMed https://www.nature.com/articles/s43587-021-00082-y