citric acid/lactic acid/potassium bitartrate (Phexxi, Evofem)

Introduction

• indications:
  • on demand non-hormonal vaginal contraceptive

Dosage

• 5 grams of Phexxi vaginal gel up to 1 hour prior to intercourse

Adverse effects

• vulvovaginal burning sensation
• vulvovaginal pruritus
• vulvovaginal mycotic infection
• urinary tract infection
• bacterial vaginosis
• vaginal discharge
• dysuria
• vulvovaginal pain

Mechanism of action

• vaginal pH regulator

More general terms

• contraceptive
• pharmacologic combination

Components

• citrate (citric acid)
• lactic acid (Lac-Hydrin)
• potassium bitartrate; potassium hydrogen tartrate; KC4H5O6; cream of tartar