osilodrostat (Isturisa)
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Introduction
Indicsations:
- treatment of Cushing's disease
Dosage
Adverse effects
- adrenal insufficiency, hypocortisolism
- headache
- nausea, vomiting
- fatigue
- edema
- QTc prolongation
- excess androgens
Mechanism of action
- inhibits 11-beta-hydroxylase thus inhibits cortisol synthesis
More general terms
References
- ↑ FDA News Release. March 6, 2020 FDA Approves New Treatment for Adults with Cushing;s Disease. https://www.fda.gov/news-events/press-announcements/fda-approves-new-treatment-adults-cushings-disease