limbic-predominant age-related TDP-43 encephalopathy (LATE)
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Epidemiology
- 20% of people older than > 80 years
Pathology
- proteinopathy of advanced age, especially > 80 years
- disease-specific cognitive impairment ... of the Alzheimer's disease type
- involves TAR DNA-binding protein 43 (TDP-43)
More general terms
Additional terms
References
- ↑ Nelson PT, Dickson DW, Trojanowksi JQ et al Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. April 30, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31039256 https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awz099/5481202
- ↑ Abbasi J Debate Sparks Over LATE, a Recently Recognized Dementia. JAMA. Published online August 21, 2019. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31433447 https://jamanetwork.com/journals/jama/fullarticle/2748914