zinc chloride (ZnCl2)

Indications

• zinc supplement for zinc deficiency
• may promote wound healing in patients with pressure ulcers
• acrodermatitis enteropathica

Dosage

• RDA: 15 mg elemental Zn+2/day
• zinc deficiency: 110-220 mg (25-50 mg elemental Zn+2) TID

Pharmacokinetics

• poor (20-30%) absorption from GI tract
• elimination mostly in feces

Adverse effects

• hypotension
• nausea/vomiting
• indigestion
• neutropenia
• leukopenia

Drug interactions

• tetracycline: decreased effect of tetracycline
• iron, bran products, dairy products: reduced absorption of Zn+2

• drug interaction(s) of diuretics in combination with Zn+2

Mechanism of action

• cofactor for more than 70 enzymes

More general terms

• zinc supplement

Additional terms

• Zn+2

Component of

• benzocaine/menthol/zinc chloride
• epinephrine/zinc chloride
• benzocaine/zinc chloride
• benzocaine/cetylpyridinium/zinc chloride
• benzocaine/cetylpyridinium/menthol/zinc chloride
• benzalkonium/hexylresorcinol/zinc chloride
• chromous chloride/zinc chloride
• benzalkonium/benzocaine/zinc chloride

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5727
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=71381