SIRT1 activator

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Introduction

SIRT1 activators may be of clinical importance because SIRT1 appears to be a principal downstream modulator of calorie restriction.

Sirt1 activators include:

More general terms

References

  1. Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007 Nov 29;450(7170):712-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18046409