becaplermin (Regranex)

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Introduction

Tradename: Regranex. Recombinant platelet-derived growth factor-beta (PDGF-beta).

Indications

Dosage

Adverse effects

* Boxed warning:

  • may be an increased risk of death from cancer in diabetic patients using Regranex (becaplermin) Gel[2]

* Boxed warning removed; no increased risk[3]

Mechanism of action

More general terms

References

  1. Ortho-McNeil Pharmaceuticals
  2. 2.0 2.1 FDA MedWatch http://www.fda.gov/medwatch/safety/2008/safety08.htm#Regranex
  3. 3.0 3.1 FDA approves removal of boxed warning from REGRANEX<TM> (becaplermin) gel, 0.01% as multiple studies demonstrate product safety. http://www.smith-nephew.com/news-and-media/media-releases/news/fda-approves-removal-of-boxed-warning-from-regranex-becaplermin-gel-001-as-multiple-studies-demonstrate-product-safety/