hepatitis B core antibody (HBcAb total) in serum

From Aaushi
Jump to navigation Jump to search

Etiology

Clinical significance

  • HBcAb total rises with HBcAb IgM, but remains elevated (regardless of whether or not the patient develops chronic hepatitis B)
  • HBcAb often remain elevated for life although titers of HBcAb may decline or disappear
  • isolated anti-HBc in the absence of HBsAb or HBsAg is common in HIV-infected patients[4]

More general terms

More specific terms

Additional terms

Component of

References

  1. Laboratory Medicine: Test Selection & Interpretation. Howanitz & Howanitz (eds), Churchill Livingstone, NY, 1991, pg 818-19
  2. Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 18. American College of Physicians, Philadelphia 2009, 2012, 2018.
  3. Hepatitis B Core Antibodies, Total Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0020091.jsp http://ltd.aruplab.com/tests/pub/0020091 https://ltd.aruplab.com/Tests/Pub/0020091
  4. 4.0 4.1 Witt MD et al. Predictors of the isolated hepatitis B core antibody pattern in HIV-infected and -uninfected men in the Multicenter AIDS Cohort Study. Clin Infect Dis 2012 Nov 30; PMID: https://www.ncbi.nlm.nih.gov/pubmed/23090927