free hydroxyproline/creatinine in urine

Indications

• assessment of bone resorption (urine)
  • acromegaly
  • hyperthyroidism
  • hyperparathyroidism
  • Paget's disease of bone
  • rickets, osteomalacia
  • bone fracture
  • bony metastases
  • osteoporosis
  • sarcoidosis
  • severe burns
  • acute osteomyelitis
  • congenital hypophosphatasia
  • fibrous dysplasia
  • growth spurts
• assessment of imminoglycinuria

Clinical significance

• measure of collagen turnover

More general terms

• urine creatinine ratio

Additional terms

• 4-hydroxyproline

Components

• free hydroxyproline in urine
• creatinine in urine