plasma cell leukemia

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^[1]

Etiology

primary disease
leukemic phase of multiple myeloma^[1]

Epidemiology

rare

Pathology

plasmacytomas

Clinical manifestations

multiple exophytic subcutaneous lesions involving the arms & legs^[1] (image)

Laboratory

complete blood count
- anemia, thrombocytopenia, leukocytosis
peripheral smear - 25% plasma cells (histopathology)^[1]

Complications

sepsis with multiorgan failure^[1]

Management

comfort care^[1]

More general terms

Additional terms

multiple myeloma; plasmacytoma/plasma cell myeloma

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Khan U, Hadid T (image, histopathology) Plasmacytomas and Plasma-Cell Leukemia. N Engl J Med 2017; 376:e19. March 16, 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28296609 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMicm1611205

Patient information

plasma cell leukemia patient information

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