pharmaceutical anticoagulant
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Indications
Contraindications
Adverse effects
- hemorrhage
- GI bleed
- coadministriation of proton pump inhibitor may decrease risk of GI bleed[5]
- hemorrhagic stroke
- GI bleed
Management
- in general, continue anticoagulant during procedures with low risk of bleeding (upper endoscopy, dental precedure, skin surggery, or cataract extraction
- for warfarin, check INR 24-72 hours before the procedure
- in general, stop most anticoagulants before a colonoscopy due to increased risk of bleeding with polypectomy
- if polypectomy is not performed, restart antithrombotics immediately following the procedure.
- if polypectomy is performed
- restart warfarin about 12 hours after the procedure
- restart dabigatran, rivaroxaban, apixaban about 48-72 hours after the procedure
More general terms
More specific terms
- anisindione (Miradon)
- bivalirudin (Angiomax)
- coagulation factor Xa inhibitor
- coumarin; chromen-2-onel cumarin; 1,2-benzopyrone; tonka bean camphor (Rattex)
- danaparoid (Orgaran)
- dicumarol (dicoumarol)
- direct oral anticoagulant; novel oral anticoagulant (DOAC, NOAC)
- fondaparinux (Arixtra)
- heparin
- heparinoid
- phenprocoumon (Marcoumar, Marcumar, Falithrom)
- thrombin inhibitor
- warfarin (Coumadin, Panwarfin, Jantoven)
Additional terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ Prescriber's Letter 18(10): 2011 Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=271020&pb=PRL Comparison of Oral Anticoagulants and Antiplatelets (subscription needed) http://www.prescribersletter.com
Prescriber's Letter 18(12): 2011 Comparison of Oral Antithrombotics Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=271220&pb=PRL (subscription needed) http://www.prescribersletter.com - ↑ Prescriber's Letter 19(12): 2012 Comparison of Oral Antithrombotics Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=281222&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ Prescriber's Letter 20(5): 2013 Managing Antithrombotics Before Minor Procedures Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=290521&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 5.0 5.1 Ray WA, Chung CP, Murray KT et al Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding. JAMA. 2018;320(21):2221-2230 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30512099 https://jamanetwork.com/journals/jama/fullarticle/2717474