antithrombin 3 antigen in plasma

Introduction

Reference range:

• adults: 19-30 mg/dL (antigenic assay)

Clinical significance

• see antithrombin-3 assay

Increases

• see antithrombin-3 assay

Decreases

• see antithrombin-3 assay

Methods

• antigenic assay: fixed rate time nephelometry

Specimen

• plasma, sodium citrate (light blue-top).
• minimal volume 0.5 mL.
• antigenic assay
  • do not thaw & refreeze
  • patient should abstain from anabolic steroids, gemfibrozil, warfarin, heparin, asparaginase, estrogens, gestodene & oral contraceptives for 3 days prior to specimen collection
  • shipping: refrigerated, frozen
  • stability:
  • room temp = 6 hours
  • refrigerated = 3 days
  • frozen = 3 weeks

More general terms

• antithrombin 3 in plasma (antithrombin 3 assay)

Additional terms

• antithrombin-III (ATIII, heparin cofactor, SERPINC1, AT3, PRO0309)