miR-126
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Function
- silencing of miR-126 in breast cancer stem cells facilitates attachment of the malignant stem cells to endothelial cells, invasion of stromal tissue at sites of metastases, & angiogenesis to promote growth of the metastatic tumor
- signals from endothelial cells seem important in silencing miR-126
More general terms
References
- ↑ Png KJ et al. A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 2011 Dec 14; 481:190. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22170610