HBO1 complex

Function

• histone H4-specific acetyltransferase activity
• reduced activity toward histone H3
• responsible for the bulk of histone H4 acetylation in vivo
• through chromatin acetylation, may function in DNA replication

Structure

• subunits include: ING4 or ING5, KAT7/HBO1, MEAF6, & one of PHF15, PHF16 or PHF17

More general terms

• molecular complex