sincalide (Kinevac)
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Indications
- to stimulate gallbladder contraction
- to stimulate pancreatic secretion
- to accelerate the transit of a barium meal through the small bowel
Dosage
- 0.02-0.04 ug/kg IV over 30-60 seconds
Adverse effects
- common
- less common <= 2%
- vomiting, flushing, sweating, rash, hypotension, hypertension, shortness of breath, urge to defecate, headache, diarrhea, sneezing, numbness
Mechanism of action
- synthetically-prepared C-terminal octapeptide of cholecystokinin