interleukin-10 receptor (IL10 receptor)

Function

• receptor for interleukin-10 (IL10)
• IL10 signaling induces phosphorylaton of STAT3

Structure

• tetramer of 2 units of IL10RA & 2 units of IL10RB

Pathology

• defects in subunits IL10RA, IL10RB found in infantile-onset Crohn's disease

More general terms

• interleukin receptor
• multisubunit protein

Additional terms

• interleukin-10; IL-10; cytokine synthesis inhibitory factor; CSIF (IL10)