HIV1/hepatitis C-coinfection
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Laboratory
- normal serum ALT not associated with less extensive hepatic fibrosis (in contrast to patients with only HCV)[1]
Complications
- increased risk for progression of hepatitis B & hepatitis C in patients with HIV1 infection
- increased risk for non-Hodgkin's lymphoma[3]
Management
- referral to GI for biopsy
- referral for HCV treatment
- lamivudine protective against liver-related deaths[2]
More general terms
References
- ↑ 1.0 1.1 Gonzalez SA et al, HIV/hepatitis C virus - coinfected patients with normal alanine aminotransferase levels. J Acquired Immune Defic Syndr 2006; 41:582 PMID: https://www.ncbi.nlm.nih.gov/pubmed/166722894
- ↑ 2.0 2.1 Puoti M et al, Impact of lamivudine on the risk of liver-related death in 1,041 HBsAg- and HIV-positive individuals. Results from an inter-cohort analysis. Antir Ther 2006, 11:567 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16964824
- ↑ 3.0 3.1 Wang Q, De Luca A, Smith C et al Chronic Hepatitis B and C Virus Infection and Risk for Non-Hodgkin Lymphoma in HIV-Infected Patients: A Cohort Study. Annals of Internal Medicine. Oct 18, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27750294 <Internet> http://annals.org/aim/article/2569661/chronic-hepatitis-b-c-virus-infection-risk-non-hodgkin-lymphoma
- ↑ Coinfection with HIV and Viral Hepatitis http://www.cdc.gov/hepatitis/hiv-hepatitis-coinfection.htm