DP2/E2F complex

Function

• probably similar to DP1/E2F complex
• the DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase
• E2F-1/DP complex appears to mediate both cell proliferation & apoptosis
• forms heterodimers with E2F family members
• the complex can interact with hypophosphorylated RB1 & related proteins (RBL1 & RBL2) that inhibit the E2F transactivation domain

More general terms

• transcription factor complex
• DNA-binding protein

Additional terms

• DRTF1/E2F (DP1/E2F)