heterochromatin protein 1-binding protein 3 (protein HP1-BP74, HP1BP3)

Function

• component of heterochromatin
• may be involved in chromatin structure & function
• interacts with CBX5 (putative)
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• in the C-terminal section; belongs to the histone H1/H5 family

Compartment

nucleus (putative)

Alternative splicing

named isoforms=5

More general terms

• nuclear protein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5080
• UniProt: http://www.uniprot.org/uniprot/Q5SSJ5.html