salivary gland neoplasm
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Etiology
- benign neoplasms:
- pleomorphic adenoma (most common salivary neoplasm)
- will recur unless fully enucleated
- firm, slowly growing mass in parotid gland, palate or cheek
- pleomorphic adenoma (most common salivary neoplasm)
- malignant tumors:
- mucoepidermoid carcinoma
- adenoid cystic carcinoma
- adenocarcinoma
- may cause ulceration
- may produce facial numbness & paralysis via invasion of nerves
- risk factors for malignancy
- prior radiation therapy
- smoking
- viral infections (EBV, HIV1, HPV)
Clinical manifestations
- painless salivary gland mass most common presentation
- facial paralysis & lymphadenopathy suggest malignancy
Diagnostic procedures
Radiology
Differential diagnosis
More general terms
More specific terms
- adenoid cystic carcinoma, salivary gland
- benign salivary gland neoplasm
- malignant salivary gland neoplasm
- monomorphic adenoma
- mucoepidermoid carcinoma, salivary gland
- parotid gland neoplasm
- pleomorphic adenoma; benign mixed tumor
- Warthin's tumor; papillary cystadenoma lymphomatosum
Additional terms
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 186, 1128
- ↑ 2.0 2.1 NEJM Knowledge+ Question of the Week Sept 29, 2020 https://knowledgeplus.nejm.org/question-of-week/391/
Kessler AT, Bhatt AA. Review of the major and minor salivary glands, part 2: neoplasms and tumor-like lesions. J Clin Imaging Sci 2018; 8:48 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30546932 PMCID: PMC6251244 Free PMC article