Streptococcus (Enterococcus) faecium
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Epidemiology
- vancomycin-resistant Enterococcus faecium spreads within & between hospital wards & between hospitals[3]
- hospital Enterococcus faecium becoming increasingly tolerant of alcohol-based hand sanitizers[4]
Laboratory
Management
- bacteremia (IV)
- ampicillin 2 g IV every 4 hours
- ampicillin plus aminoglycoside for synergy if sepsis or cardiac valve abnormality
- ampicillin-resistance is common
- Vancomycin 1 g IV every 14 hours
- vancomycin resistance frequently accompanies ampicillin- resistance
- doxycycline has in vitro activity against some forms of vancomycin-resistant Enterococcus (VRE)
- Synercid (VRE)
- linezolid (Zyvox)
- duration of therapy 7-10 days unless otherwise indicated (i.e. endocarditis)
More general terms
Additional terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ UpToDate version 15.2 http://www.utdol.com
- ↑ Jump up to: 3.0 3.1 Raven KE, Gouliouris T, Brodrick H et al. Complex routes of nosocomial vancomycin-resistant Enterococcus faecium transmission revealed by genome sequencing. Clin Infect Dis 2017 Apr 1; 64:886 PMID: https://www.ncbi.nlm.nih.gov/pubmed/28362945 https://academic.oup.com/cid/article/3051757/Complex
- ↑ Jump up to: 4.0 4.1 Pidot SJ, Gao W, Buultjens AH et al Increasing tolerance of hospital Enterococcus faecium to handwash alcohols. Science Translational Medicine. Aug 1, 2018: 10(452):eaar6115 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/30068573 <Internet> http://stm.sciencemag.org/content/10/452/eaar6115