neurofilament protein

Function

• neurofilament proteins M & H are highly phosphorylated

Structure

• neurofilaments usually contain 3 intermediate filament proteins:
  • neurofilament L
  • neurofilament M
  • neurofilament H
• extra mass & high charge density due to tailpiece extensions distinguish neurofilament proteins from all other intermediate filament proteins; this region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions

More general terms

• intermediate filament protein
• PEST protein

More specific terms

• alpha-internexin (alpha-Inx, 66 kD neurofilament protein, neurofilament-66, NF-66, INA)
• neurofilament heavy polypeptide; NF-H; neurofilament triplet H protein; 200 kD neurofilament protein (NEFH, KIAA0845, NFH)
• neurofilament light polypeptide; NF-L; neurofilament triplet L protein; 68 kD neurofilament protein (NEFL, NF68, NFL)
• neurofilament medium polypeptide; NF-M; neurofilament triplet M protein; 160 kD neurofilament protein; neurofilament 3 (NEFM NEF3 NFM)

Component of

• neurofilament