neurofilament

Function

• neurofilaments may form from neurofilament L & either neurofilament M or neurofilament H
• neurofilaments within perikarya & proximal dendrites are normally minimally phorphorylated
• in contrast, neurofilaments in axons are normally heavily phosphorylated

Structure

• cytoskeletal filaments:
  • microtubules: 25 nm
  • intermediate filaments: 10-12 nm (includes neurofilaments)
  • microfilaments: 7-10 nm

More general terms

• intermediate filament

Additional terms

• neurofilament disorder