oxaloacetate

Biochemistry

• intermediate in the citric acid cycle
• formed from malate via malate dehydrogenase*
  • enzyme: malate dehydrogenase
  • substrates: malate + NAD+
  • products: oxaloacetate + NADH
• metabolized to citrate via citrate synthase*
  • enzyme: citrate synthase
  • substrates: oxaloacetate + acetyl-CoA
    • products: citrate + Coenzyme-A

* see citric acid cycle for role of malate in citric acid cycle

More general terms

• oxalate
• ketone

Additional terms

• citric acid cycle, Krebs cycle or tricarboxylic acid [TCA] cycle
• gluconeogenesis

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=970