fluorescein (Fluor-I-Strip, Fluress, Funduscein, AK-Fluor, Fluorescite, Ful-Glo)
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Indications
- demonstration of defects in corneal epithelium
- diagnostic aid in ophthalmic angiography
Dosage
- solution
- 1-2 drop of 2% solution
- allow to stand for a few seconds
- wash out excess with irrigation solution
- strips
- moisten strip with sterile water
- place strip at fornix into the lower cul-de-sac close to the punctum
- injection
- MUST perform intradermal skin test prior to use
- usual dose: 500-750 mg in antecubital vein
Injection: 10% (5 mL), 25% (3 mL) Strip ophthalmic 1 mg (300s); 9 mg (300s) Solution ophthalmic: (Fluress) 0.25% with benoximate HCl 0.4% (5 mL)
Adverse effects
- not common (1-10%)
- temporary stinging, burning, irritation
- uncommon (< 1%)
- other
- extravasation results in local tissue damage
- soft contact lenses will become discolored
- skin stains for about 6-12 hours
- urine stains for about 24-36 hours CAUTIONS:
- do NOT replace contact lenses for at least 1 hours
- flush out eye prior to replacement of contact lenses
Mechanism of action
- water-soluble dye
- penetrate any break in epithelial barrier