sulforaphane

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Introduction

Potent inducer of phase 2 drug metabolizing enzymes with anti-carcinogenic properties.

Occurs naturally in broccoli & brussel sprouts.

Indications

(possible uses)

 O=S-(CH2)4-N=C=S
   |
   CH3

Mechanism of action

More general terms

References

  1. Merck Index, I2th ed, Merck & Co, Rahway NJ, 1996 # 9315
  2. Netscape 07/14/04 sites evidence from researchers at Johns Hopkins University
  3. Egner PA et al Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China. Cancer Prevention Research. August 2014 7; 813 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24913818 <Internet> http://cancerpreventionresearch.aacrjournals.org/content/7/8/813
  4. 4.0 4.1 Axelsson AS, Tubbs E, Mecham B Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes. Sci Transl Med. 2017 Jun 14;9(394). PMID: https://www.ncbi.nlm.nih.gov/pubmed/28615356
  5. Gever J Really, Soup Might Help in Osteoarthritis? Not just any soup. And no chicken needed. MedPage Today. June 24, 2024 https://www.medpagetoday.com/rheumatology/arthritis/110794
    Davidson RK, Watts L, Beasy G et al The BRoccoli In Osteoarthritis (BRIO study) - A randomised controlled feasibility trial to examine the potential protective effect of broccoli bioactives, (specifically sulforaphane), on osteoarthritis. medRxiv 2024. June 21. https://www.medrxiv.org/content/10.1101/2024.06.20.24309233v1

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