anagrelide (Agrylin)

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Introduction

Tradename: Agrylin.

Indications

Dosage

  • start 0.5 mg PO QID,
  • after 1 week, adjust to lowest effective dose
  • maximum: 10 mg/day

Tabs: 0.5 & 1 mg.

Pharmacokinetics

elimination via liver

elimination via kidney

1/2life = 1.3-1.8 hours

Monitor

Adverse effects

Mechanism of action

More general terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  3. Physician's Desk Reference (PDR) 52nd edition, Medical Economics, 1998
  4. 4.0 4.1 Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Liver Function Test Scheduling Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=260704&pb=PRL (subscription needed) http://www.prescribersletter.com
  5. 5.0 5.1 Deprecated Reference

Database