iodoquinol; diiodohydroxyquin (Yodoxin)

Introduction

Tradename: Yodoxin.

Indications

• treatment of acute & chronic intestinal amebiasis
• asymptomatic individuals passing parasitic cysts
• Blastocystis hominis infection

Dosage

• adults: 650 mg PO TID for 20 days
• children: 30-40 mg/kg/day divided TID for 20 days, max: 1.95 g/day (650 mg/dose)

Tabs: 210 & 650 mg.

Adverse effects

• common (> 10%)
  • diarrhea, nausea/vomiting, stomach pain
• less common (1-10%)
  • fever/chills, rash, hives, enlargement of thyroid gland, headache, rectal itching, peripheral neuropathy, agitation, retrograde amnesia, weakness, optic neuritis, optic atrophy, visual impairment

More general terms

• quinoline; leucoline; chinoleine; 1-benazazine; benzo[b]pyridine
• amebicide

Component of

• aloe vera/iodoquinol
• aloe vera/cortisol/iodoquinol
• iodoquinol/polysaccharide
• cortisol/iodoquinol (Vytone)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3728