altretamine (Hexalen)

Introduction

Tradename: Hexalen.

Indications

• palliative treatment of persistent or recurrent ovarian cancer

Dosage

capsule 50 mg

Adverse effects

• common (> 10%)
  • peripheral sensory neuropathy
  • neurotoxicity
  • nausea/vomiting
  • anemia
  • thrombocytopenia
  • leukopenia
• not common (1-10%)
  • seizures, anorexia, diarrhea, stomach cramps, increased alkaline phosphatase
• uncommon (< 1%)
  • dizziness, depression, rash, alopecia, myelosuppression, hepatotoxicity, tremor

• drug adverse effects of alkylating agents

More general terms

• alkylating agent

Additional terms

• ovarian cancer

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2123