argyrophilic grain disease (AgD)

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Epidemiology

  • disorder of the elderly, incidence increases with age
  • approximately 5% of all cases of dementia

Pathology

Genetics

Clinical manifestations

  • clinically distinct from PSP & CBD
  • shares features of mild AD

More general terms

References

  1. Probst A, Tolnay M. [Argyrophilic grain disease (AgD), a frequent and largely underestimated cause of dementia in old patients] Rev Neurol (Paris). 2002 Feb;158(2):155-65. Review. French. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11965171
    Tolnay M, Clavaguera F. Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies. Neuropathology. 2004 Dec;24(4):269-83. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15641585

Patient information

argyrophilic grain disease patient information