sudden infant death syndrome (SIDS); includes; accidental infant strangulations & suffocations

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Etiology

  • risk factors may be age-dependent[10]
    • predominant risk factor for younger infants is bed-sharing
    • whereas rolling to prone, with objects in the sleep area, is the predominant risk factor for older infants
  • other risk factors[6]
  • accidental strangulation & suffocation[16]
    • mean age at death was 3.8 months
    • sleep location: crib or bassinet (31%), adult bed (23%), sofa or chair (19%)
    • position: wedged (43%), on top of an object (26%), covered (8%)
    • implicated objects: pillows (25%), mattresses (21%), blankets (13%), walls (12%)
    • sleep surface sharing
      • infant position was most frequently overlaying by an adult or child (51%) or wedging (45%)
      • location was usually a sofa or chair (74%)[16]

Epidemiology

  • incidence 76/100,000 live births in 1998 USA
    • incidence has increased from 12 to 28 per 100,000 people 1999-2015[19]
  • > 50% of U.S. infants sleep with blankets, pillows, or other potentially dangerous bedding despite recommendations against this[12]
  • < 1/2 of women always place infant in supine position to sleep[17]
    • black (vs white) women & womwn who did not complete high school more likely to place infant in prone position[17]
  • unsafe infant sleep habits are still common[18]
    • 22% of mothers most often put infant to sleep on their side or stomach
    • nonsupine infant positioning highest among non-Hispanic blacks, younger & less educated mothers
    • 2/3 of mothers share bed with infant
    • 1/3 of mothers use soft bedding like bumpers in the crib

Pathology

Genetics

Differential diagnosis

child abuse[4]

Management

More general terms

More specific terms

Additional terms

References

  1. Journal Watch 22(8):62, 2002 McMartin KI et al, J Pediatr 140:205, 2002
  2. 2.0 2.1 Journal Watch 23(13):105, 2003 Hunt CE et al, Arch Pediatr Adolesc Med 157:469, 2003
  3. Journal Watch 24(10):83, 2004 Getahun D, Amre D, Rhoads GG, Demissie K. Maternal and obstetric risk factors for sudden infant death syndrome in the United States. Obstet Gynecol. 2004 Apr;103(4):646-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15051553
  4. 4.0 4.1 4.2 Hauck FR, Omojokun OO, Siadaty MS. Do pacifiers reduce the risk of sudden infant death syndrome? A meta-analysis. Pediatrics. 2005 Nov;116(5):e716-23. Epub 2005 Oct 10. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16216900
  5. 5.0 5.1 Li D-K et al, Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study BMJ 2006; 332:18 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16339767
  6. 6.0 6.1 Blair PS et al. Major epidemiological changes in sudden infant death syndrome: A 20-year population-based study in the UK. Lancet 2006 Jan 28; 367:314-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16443038
  7. Hymel KP. Distinguishing sudden infant death syndrome from child abuse fatalities. Pediatrics. 2006 Jul;118(1):421-7. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/16818592 <Internet> http://aappolicy.aappublications.org/cgi/content/full/pediatrics;118/1/421
  8. 8.0 8.1 Paterson DS et al, Multiple serotonergic brainstem abnormalities in sudden infant death syndrome. JAMA 2006, 296:2124 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17077377
    Weese-Mayer DE, Sudden infant death syndrome: Is serotonin the key factor? JAMA 2006, 296:2143 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17077381
  9. 9.0 9.1 Duncan JR et al. Brainstem serotonergic deficiency in sudden infant death syndrome. JAMA 2010 Feb 3; 303:430. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20124538
  10. 10.0 10.1 10.2 Colvin JD et al Sleep Environment Risks for Younger and Older Infants. Pediatrics. July 2014 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25022735 <Internet> http://pediatrics.aappublications.org/content/early/2014/07/09/peds.2014-0401.full.pdf+html
  11. Choosing Wisely American Academy of Pediatrics Ten Things Physicians and Patients Should Question. http://www.choosingwisely.org/doctor-patient-lists/american-academy-of-pediatrics/
  12. 12.0 12.1 Shapiro-Mendoza CK et al Trends in Infant Bedding Use: National Infant Sleep Position Study, 1993-2010 Pediatrics. Dec 1, 2014 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25452654 <Internet> http://pediatrics.aappublications.org/content/early/2014/11/25/peds.2014-1793.abstract
    Moon RY, Hauck FR Hazardous Bedding in Infants' Sleep Environment Is Still Common and a Cause for Concern. Pediatrics. Dec 1, 2014 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25452652 <Internet> http://pediatrics.aappublications.org/content/early/2014/11/25/peds.2014-3218.full.pdf+html
  13. 13.0 13.1 Katz D, Shore S, Bandle B et al Sudden Infant Death Syndrome and Residential Altitude. Pediatrics. May 25, 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26009621 <Internet> http://pediatrics.aappublications.org/content/early/2015/05/20/peds.2014-2697.abstract
  14. 14.0 14.1 14.2 Pease AS, Fleming PJ, Hauck FR et al Swaddling and the Risk of Sudden Infant Death Syndrome: A Meta-analysis/ Pediatrics May 2016 PMID: https://www.ncbi.nlm.nih.gov/pubmed/27244847
  15. 15.0 15.1 15.2 15.3 15.4 15.5 Kassa H, Moon RY, Colvin JD Risk Factors for Sleep-Related Infant Deaths in In-Home and Out-of-Home Settings. Pediatrics Oct 2016, e20161124 PMID: https://www.ncbi.nlm.nih.gov/pubmed/27940776
    TASK FORCE ON SUDDEN INFANT DEATH SYNDROME SIDS and Other Sleep-Related Infant Deaths: Updated 2016 Recommendations for a Safe Infant Sleeping Environment. Pediatrics Oct 2016, e20162938; PMID: https://www.ncbi.nlm.nih.gov/pubmed/27940804
    Moon RY, TASK FORCE ON SUDDEN INFANT DEATH SYNDROME SIDS and Other Sleep-Related Infant Deaths: Evidence Base for 2016 Updated Recommendations for a Safe Infant Sleeping Environment. Pediatrics Oct 2016, e20162940 PMID: https://www.ncbi.nlm.nih.gov/pubmed/27940805
  16. 16.0 16.1 16.2 Gaw CE, Chounthirath T, Midgett J, Quinlan K, Smith GA. Types of objects in the sleep environment associated with infant suffocation and strangulation. Acad Pediatr 2017 Jul 16; PMID: https://www.ncbi.nlm.nih.gov/pubmed/28723589
  17. 17.0 17.1 17.2 17.3 Colson ER, Geller NL, Heeren T, Corwin MJ Factors Associated With Choice of Infant Sleep Position. Pediatrics. August 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28827382 <Internet> http://pediatrics.aappublications.org/content/early/2017/08/17/peds.2017-0596
    Goodstein MH, Ostfeld BM Improvements in Infant Sleep Position: We Can Do Better! Pediatrics. August 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28827378 <Internet> http://pediatrics.aappublications.org/content/early/2017/08/17/peds.2017-2068
  18. 18.0 18.1 Bombard JM, Kortsmit K, Warner L, et al. Vital Signs: Trends and Disparities in Infant Safe Sleep Practices - United States, 2009-2015. MMWR Morb Mortal Wkly Rep. ePub: 9 January 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29324729 Free PMC Article https://www.cdc.gov/mmwr/volumes/67/wr/mm6701e1.htm
  19. 19.0 19.1 Gao Y, Schwebel DC, Hu G Infant Mortality Due to Unintentional Suffocation Among Infants Younger Than 1 Year in the United States, 1999-2015. JAMA Pediatr. Published online February 19, 2018. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29459979 https://jamanetwork.com/journals/jamapediatrics/article-abstract/2672731
  20. 20.0 20.1 Anderson TM, Lavista Ferres JM, Ren SY et al. Maternal smoking before and during pregnancy and the risk of sudden unexpected infant death. Pediatrics 2019 Mar 11; PMID: https://www.ncbi.nlm.nih.gov/pubmed/30858347 https://pediatrics.aappublications.org/content/early/2019/03/07/peds.2018-3325

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