sequential organ failure assessment (SOFA, quick or qSOFA)
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Indications
- assessment of sepsis & septic shock
- qSOFA score identifies hospitalzed patients with infection at risk of death in low-income countries[3]
Clinical significance
- a qSOFA score >=2 suggests poor prognosis
- for patients who require mechanical ventilation, age predicts mortality better than SOFA score[4]
* qSOFA has poor sensitivity & moderate specificity for short-term mortality[2]
More general terms
References
- ↑ Freund Y, Lemachatti N, Krastinova E et al. Prognostic accuracy of Sepsis-3 criteria for in-hospital mortality among patients with suspected infection presenting to the emergency department. JAMA 2017 Jan 17; 317:301. http://jamanetwork.com/journals/jama/article-abstract/2598268
Raith EP, Udy AA, Bailey M et al. Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA 2017 Jan 17; 317:290. http://jamanetwork.com/journals/jama/article-abstract/2598267
Lamontagne F, Harrison DA, Rowan KM. qSOFA for identifying sepsis among patients with infection. JAMA 2017 Jan 17; 317:267. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28114531 - ↑ 2.0 2.1 Fernando SM, Tran A, Taljaard M et al. Prognostic accuracy of the quick sequential organ failure assessment for mortality in patients with suspected infection: A systematic review and meta-analysis. Ann Intern Med 2018 Feb 20; 168:266. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29404582 <Internet> http://annals.org/aim/article-abstract/2671919/prognostic-accuracy-quick-sequential-organ-failure-assessment-mortality-patients-suspected
Singer M, Shankar-Hari M. qSOFA, cue confusion. Ann Intern Med 2018 Feb 20; 168:293. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29404580 <Internet> http://annals.org/aim/article-abstract/2671920/qsofa-cue-confusion?doi=10.7326%2fM17-3415 - ↑ 3.0 3.1 Rudd KE, Seymour CW, Aluisio AR et al Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries. JAMA. Published online May 20, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29800114 https://jamanetwork.com/journals/jama/fullarticle/2681801
Adhikari NKJ, Rubenfeld GD qSOFA Score for Patients With Sepsis in Low- and Middle-Income Countries. JAMA. Published online May 20, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29800023 https://jamanetwork.com/journals/jama/fullarticle/2681800 - ↑ 4.0 4.1 Raschke RA et al. Discriminant accuracy of the SOFA score for determining the probable mortality of patients with COVID-19 pneumonia requiring mechanical ventilation. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33595630 PMCID: PMC7890534 (available on 2021-08-17) JAMA 2021 Feb 17; https://jamanetwork.com/journals/jama/fullarticle/2776737
- ↑ qSOFA (Quick SOFA Score) for Sepsis Identification https://www.mdcalc.com/qsofa-quick-sofa-score-sepsis-identification