meningeal neoplasm

Epidemiology

• see meningioma

Genetics

• chromosome 22q12 allelic loss ~1/2 cases
  • NF2 gene & SIS proto-oncogene implicated
• chromosome 1p, 6q, 9q, 10q, 14q, 17p, 18p loss often in atypical meningiomas
• chromosome 6q,9p 10 and 14q more frequently loss in anaplastic meningiomas
• meningiomas are associated with defects in MN1
• other implicated genes
  • C6orf153, AP1B1

Radiology

• magnetic resonance imaging (MRI)
• computed tomography (CT)
• see meningioma

Management

• see meningioma

More general terms

• meningeal disease
• central nervous system (CNS) neoplasm

More specific terms

• benign meningeal neoplasm
• carcinomatous meningitis (leptomeningeal metastases)
• hemangiopericytoma of meninges
• lymphomatous meningitis
• meningioma