tumor suppressor protein MN1 (meningioma chromosome region 1 protein, MGCR1)
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Expression
- ubiquitously expressed
- highest levels in skeletal muscle
Pathology
- a chromosomal translocation t(12;22)(p13;q11), MN1 with TEL is associated with acute myeloid leukemia (AML)
- defects in MN1 may be a cause of meningiomas
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q10571.html
- ↑ Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/MN1.html