acute panmyelosis with myelofibrosis

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Introduction

poorly defined disorder

Etiology

Epidemiology

  • rare
  • mostly adults

Microscopic pathology

Immunophenotype

Genetics

  • complex abnormalities
  • frequent involvement of chromosomes 5 and/or 7

Clinical manifestations

Laboratory

Differential diagnosis

Management

Notes

More general terms

References

  1. Wikipedia: Acute panmyelosis with myelofibrosis http://en.wikipedia.org/wiki/Acute_panmyelosis_with_myelofibrosis
  2. WHO Classification Tumours of Haematopoietic and Lymphoid Tissues. IARC Press 2001
  3. Bae E, Park CJ, Cho YU et al Differential diagnosis of myelofibrosis based on WHO 2008 criteria: acute panmyelosis with myelofibrosis, acute megakaryoblastic leukemia with myelofibrosis, primary myelofibrosis and myelodysplastic syndrome with myelofibrosis. Int J Lab Hematol. 2013 Dec;35(6):629-36. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23693053