refractory anemia (RA)
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Epidemiology
- 28% of cases of myelodysplastic syndrome
Pathology
- circulating blasts < 1%
- bone marrow blasts < 5%
- < 15% ringed sideroblasts in marrow
- no Auer rods
Management
- prognosis:
- 0-20% (mean 11%) transformation to acute leukemia (AML)
- survival 19-64 months (mean 37 months)
More general terms
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 677-78