pituitary adenoma/ACTH secreting

Pathology

• often basophilic appearing adenomas

Genetics

• associated with defects in AIP

Clinical manifestations

see Cushing's syndrome

Differential diagnosis

• rare abdominal or chest tumor secreting ectopic CRH

Management

• pharmaceutical agents
  • ketoconazole
  • metyrapone
  • cabergoline
  • mifepristone
  • mitotane
  • etomidate
• also see pituitary adenoma

More general terms

• pituitary adenoma

More specific terms

• Nelson's syndrome

Additional terms

• adrenocorticotropic hormone; corticotropin; adrenocorticotropin (ACTH)
• corticotropin-releasing factor; corticoliberin; CRF; corticotropin-releasing hormone (CRH)
• Cushing's syndrome; hypercortisolism; hyperadrenocorticism; pluriglandular syndrome
• ectopic ACTH syndrome

Database

• OMIM: https://mirror.omim.org/entry/219090