corticotropin-releasing factor; corticoliberin; CRF; corticotropin-releasing hormone (CRH)

Function

• regulates release of corticotropin from pituitary gland
• interacts (via C-terminus) with CRFR1 (via N-terminal extracellular domain)

Structure

• belongs to the sauvagine/corticotropin-releasing factor/ urotensin I family

Compartment

secreted

Expression

• secreted by hypothalamus

More general terms

• pituitary hormone-releasing hormone; hypothalamic hormone

Additional terms

• adrenocorticotropic hormone; corticotropin; adrenocorticotropin (ACTH)
• corticotropin-releasing factor/hormone [CRF/CRH] receptor
• corticotropin-releasing hormone (CRH) stimulation test

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1392
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1392
• OMIM: https://mirror.omim.org/entry/122560
• UniProt: http://www.uniprot.org/uniprot/P06850.html