glial-derived neurotrophic factor; hGDNF; astrocyte-derived trophic factor; ATF (GDNF)

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Function

Structure

Compartment

secreted

Expression

Pathology

More general terms

Additional terms

References

  1. Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science. 1993 May 21;260(5111):1130-2. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8493557
  2. 2.0 2.1 Trupp M et al Functional receptor for GDNF encoded by the c-ret proto- oncogene. Nature. 1996 Jun 27;381(6585):785-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657281
  3. 3.0 3.1 Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, et al. GDNF signalling through the Ret receptor tyrosine kinase. Nature. 1996 Jun 27;381(6585):789-93. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657282
  4. 4.0 4.1 Sanchez MP, Silos-Santiago I et al Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):70-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657306
  5. 5.0 5.1 Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):73-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657307
  6. 6.0 6.1 Moore MW et al Reichardt LF, Ryan AM, Carver-Moore K, Rosenthal A. Renal and neuronal abnormalities in mice lacking GDNF. Nature. 1996 Jul 4;382(6586):76-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8657308
  7. UniProt http://www.uniprot.org/uniprot/P39905.html
  8. R&D systems' cytokine mini-reviews: GDNF http://www.rndsystems.com/molecule_detail.aspx?m=1510
  9. GeneReviews http://www.ncbi.nlm.nih.gov/sites/genetests/lab/gene/GDNF

Database