ESCRT-1 complex; endosomal sorting complex required for transport 1

Function

• regulator of vesicular trafficking

Structure

• subunits: TSG101, VPS28, a VPS37 protein (VPS37A, VPS37B, VPS37C, VPS37D) & MVB12A or MVB12B in a 1:1:1:1 stoechiometry

More general terms

• molecular complex

Components

• multivesicular body subunit 12B; ESCRT-I complex subunit MVB12B; protein FAM125B (MVB12B, C9orf28, FAM125B)