RNA polymerase 2 elongator complex

Function

• histone acetyltransferase component of RNA polymerase 2 holoenzyme
• associates with the C-terminal domain RNA polymerase 2 L' (RBP1)
• involved in transcriptional elongation
• role in chromatin remodeling
• role in acetylation of histones H3 & probably H4

Structure

• subunits:
  • KBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, p30 & p38

More general terms

• molecular complex