interferon [IFN] gamma receptor

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Introduction

Putative receptor associated molecule, so far unidentified [From ref 1]. It is assumed that IFN-gamma receptor alpha is identical to the IFN-gamma receptor in ref 1 & that IFN-gamma receptor beta is the accessory factor. Both JAK1 & JAK2 must be present for functional activation via the IFN-gamma receptor.

More general terms

References

  1. Taga T & Kishimoto T Cytokine receptors and signal transduction FASEB J 6:3387 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1334470
  2. Ihle JN et al Signaling by the cytokine receptor superfamily: JAKs and STATs TIBS 19:222 1994 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8048164