Janus kinase 1 (tyrosine-protein kinase JAK1, JAK-1, JAK1, JAK1A, JAK1B)

From Aaushi
Jump to navigation Jump to search

Function

Structure

Compartment

Pharmacology

More general terms

References

  1. Ihle JN et al Signaling by the cytokine receptor superfamily: JAKs and STATs TIBS 19:222 1994 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8048164
  2. 2.0 2.1 UniProt http://www.uniprot.org/uniprot/P23458.html
  3. 3.0 3.1 McNamara D JAK-1 Inhibitor Effective for RA, but Safety Signal Troubles. Medscape - Nov 13, 2017. https://www.medscape.com/viewarticle/888522
  4. Genovese MC, Kalunian K, Gottenberg JE et al Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease- Modifying Antirheumatic Drug TherapyThe FINCH 2 Randomized Clinical Trial. JAMA. 2019;322(4):315-325 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31334793 https://jamanetwork.com/journals/jama/fullarticle/2738551
    Singh JA Filgotinib, a JAK1 Inhibitor, for Treatment-Resistant Rheumatoid Arthritis. JAMA. 2019;322(4):309-311 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31334773 https://jamanetwork.com/journals/jama/fullarticle/2738528

Database