CD72; B-cell differentiation antigen CD72; Lyb-2 (CD72)

Function

• may control B cell proliferation & differentiation
• associates with CD5

Structure

• homodimer; disulfide-linked
• contains 1 C-type lectin domain

Compartment

plasma membrane

Expression

• exclusively B cells
• pre-B-cells & B-cells but not terminally differentiated plasma cells

Pathology

• expressed in hairy cell leukemia

More general terms

• CD antigen
• glycoprotein
• lectin

Database

• UniProt: http://www.uniprot.org/uniprot/P21854.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=971
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:971
• OMIM: https://mirror.omim.org/entry/107272