bcl-xS
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Function
- enhances apoptosis
- antagonizes bcl-2 induced resistance to apoptosis
Structure
- the bcl-xS alternatively spliced form with 63 amino acids in bcl-xL deleted (Val-126 - Trp-188)
- this would clip out the BH1 domain & 1/2 of the BH2 domain
More general terms
References
- ↑ Boise LH et al bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 1993 Aug 27;74(4):597-608. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8358789